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Afatinib API
API
GS.25.AFT.00.png
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Product Name Afatinib API
Product Category Pharmaceutical API's
Sub-Category Heterocycles, Pharmaceutical Standards, Fine Chemicals, Chiral Standards, Amines
CAS No 850140-72-6
Catalog Number GS.25.AFT.00
Chemical Name/Synonyms (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide; 850140-73-7 (Dimaleate salt)
Molecular Weight 485.94
Molecular Formula C24H25ClFN5O3
Purity NLT 98 %
Appearance Pale yellow to light beige crystalline powder
Solubility Ethanol, DMSO
Applications afatinib is a protein kinase inhibitor, it is used for the treatment of patients with distinct types of metastatic (EGFR mutation positive) non-small cell lung carcinoma (NSCLC), developed by Boehringer Ingelheim. It is also known as Gilotrif and Giotrif.
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