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Impurity of Abacavir API
Abacavir EP Impurity A
Impurity
GS.01.ABA.01_1779698112.png
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Product Name Abacavir EP Impurity A
Product Category Impurities, Intermediates
Sub-Category Pharmaceutical Standards, Enzyme Inhibitors, Bases and Related Reagents, Nucleotides, Fine Chemicals
CAS No 136470-79-6
Catalog Number GS.01.ABA.01
Chemical Name/Synonyms ent-Abacavir; [(1R,4S)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl]methanol; [(1R,4S)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-enyl]methanol; (1R,4S)-Abacavir;(1R-cis)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol; ((1R,4S)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol; 935777-88-1 (sulfate salt)
Molecular Weight 286.33
Molecular Formula C14H18N6O
Purity NLT 95%
Appearance Colourless Solution
Solubility Methanol, DMSO
Applications Ent-abacavir is also used as part of active antiretroviral therapy, which includes at least three or four different drugs. It inhibits the activity of reverse transcriptase, an enzyme involved in the replication process of HIV and other retroviruses.
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